Archive for October, 2009

Comparison of topical 5-fluorouracil formulations in actinic keratosis treatment.

J Dermatolog Treat. 2009 Nov 1;
Kaur RR, Alikhan A, Maibach HI

Abstract Background: Actinic keratoses (AKs) are common and may progress to squamous cell carcinoma (SCC). While cryotherapy is the most commonly used treatment for AKs, it is only suitable for treating a few lesions at a time. Topical medications such as 5-fluorouracil (5-FU) allow for more generalized treatment of AKs in the setting of multiple lesions. Objective: To evaluate and discuss clinical trials examining the efficacy of 5-FU cream formulations (0.5% and 5%), as 5% 5-FU has four times greater systemic absorption. Methods: We conducted Pubmed and Embase searches (1965 to 13 April 2009) to find studies evaluating the efficacy of 5-FU cream monotherapy (0.5% and 5%) in treating multiple AKs of the face and scalp. We only included studies employing standard treatment regimens (as per the US FDA), with an endpoint of complete clearance. Results: Nine studies met our criteria. At 4 weeks post-treatment, complete clearance rates of 0.5% and 5% 5-FU ranged from 16.7% to 57.8% and 43% to 100%, respectively. As the various studies employed different measurements of tolerability, we were unable to pool this data. In the only split-face study comparing both formulations, both treatments produced equivalent rates (43%) of complete clearance, but 5% 5-FU had higher rates of adverse events. Conclusions: Despite evidence suggesting the superior efficacy of 5% 5-FU over 0.5% 5-FU, high-powered clinical trials comparing both treatments are lacking. Furthermore, tolerability rates between formulations warrant further examination given the possible enhanced systemic absorption of 5% 5-FU over 0.5% 5-FU. Such studies will enable dermatologists to appropriately balance the risks and benefits of each respective treatment to provide optimal solutions to patients with multiple AKs.
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Anyone own the Tobi Steamer – Wrinkle Remover as seen on TV? Can you give a review of this product? Thanks.?

I am interested in Tobi but want to know how it is.

Here is the video presentation
http://www.thetobi.com

nope don’t own one!

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Starting up a new bath and body all natural products looking for a name for products?

I came up with a few wondered if these names are any good.Is The body buffet, organic body, lush body or body lush good names or can anyone one suggest something else?

the body buffet sounds good, you should use it.

here are my suggestions:

body by nature
naturelle
natureal

Good luck!

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Is there a good wrinkle remover or will botox work on a very wrinkled B-Hole?

Mine just looks so old.

Arbonne hasanti aging products that work. They have this serum that rejuvenates your skin and dimminish lines. They also have a temporary fix for the day out .it’s the transforming lift.
here is a link you can look at
http://myladybeau.myarbonne.com

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Is there a good wrinkle remover or will botox work on a very wrinkled B-Hole?

Mine just looks so old.

Arbonne hasanti aging products that work. They have this serum that rejuvenates your skin and dimminish lines. They also have a temporary fix for the day out .it’s the transforming lift.
here is a link you can look at
http://myladybeau.myarbonne.com

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Whats the best antiaging product for men?


I would suggest the Mary Kay Time Wise Skin care and skin supplement line. The results are guaranteed or your money refunded

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Whats the best antiaging product for men?


I would suggest the Mary Kay Time Wise Skin care and skin supplement line. The results are guaranteed or your money refunded

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i need a natural facial moisturizer from a store like wallmart?

or Rite-Aid? like whats a brand of natural oil free moisturizer? cuz my skin is irritated from all the chemicals i use i want something natural and soothing from redness that i can find at a store? can any1 help?

Nivia soft… It is the best ever… Works on my oily skin and prvents olily skin..

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i need a natural facial moisturizer from a store like wallmart?

or Rite-Aid? like whats a brand of natural oil free moisturizer? cuz my skin is irritated from all the chemicals i use i want something natural and soothing from redness that i can find at a store? can any1 help?

Nivia soft… It is the best ever… Works on my oily skin and prvents olily skin..

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How can get my natural skin care product listed on NHS So it can be perscribed by Doctors @ the Chemists?


I think it needs to go through a series of rigorous testing procedures before the NHS would touch it, I know the big pharmaceutical companies have to test their products for years, and then they hold clinical trials, and then the product is released.

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